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ERECTILE DYSFUNCTION:
Some statistics and options


This pie chart from the Clinical Diabetes journal (1998) shows the major causes of ED in the United States.

This is why other fields (such as diabetes) have studied the problem and can provide valuable information as well as potential solutions.

(from "Erectile Dysfunction in Diabetes: Pills for Penile Failure" in Clinical Diabetes journal, 1998, No. 3. See below.)
pie chart showing statistics: Vascular 40% Diabetes melitus 30% Radical surgery 13% Spinal cord injury and other traumas 8% Other endocrine problems 6% Multiple sclerosis 3%





Some Therapeutic Options for Erectile Dysfunction

Medication Action Use Pros and Cons
Viagra (sildenafil) Relaxes smooth muscle in corpora Taken 1 hour before sex, requires stimulation Headache, diarrhea, flushing, hypotension, disturbed color vision. Greatest help with partial ED
Spontane (apomorphine)
In final trials
CNS stimulant that triggers erections (dopa-minergic) Works in up to one-third of mild cases Requires stimulation.
Vasomax (phentolamine)
Under FDA review
Alpha-adrenergic antagonist relaxes smooth muscle and increases blood flow Taken 20–40 minutes before sex. Helps 60–80% of those tested. Requires stimulation.
Fewer side effects than sildenafil.
MUSE (alprostadil)
Approved 1997
Applicator inserted into urethra Applied 5–10 minutes before sex. Erection lasts 1 hour Can be used 2 times/day.
Not for use with pregnant partner.
Caverject (alprostadil)
Approved 1997
Injected into corpus cavernosa. Relaxes smooth muscle and dilates blood vessels Injected 20 minutes before sex. Lasts >1 hour. Effective >50%. May be very painful.
Cannot be used every day.
Edex (alprostadil) Different formulation alprostadil Injected with smaller needle. Injected 10 minutes to 2 hours before sex. Erections last >1 hour. Cheaper than Caverject.
Invicorp (VIP and phentolamine).
FDA submission 1998
Relaxes smooth muscle Just before sex. More effective than either agent above. Requires stimulation.
No pain.
Vacuum pumps
Approved 1982
Draws blood into corpora by negative pressure Just before sex.
Erections last until elastic ring removed
Clumsy. Interferes with foreplay. Difficult ejaculation.
Penile implants
Since 1966
Rigid or malleable rod or inflatable Bent or pumped into erect state Destroys erectile tissue. Complications high in diabetes.
Rods embarrassing.
(from "Erectile Dysfunction in Diabetes: Pills for Penile Failure" in Clinical Diabetes journal, 1998, No. 3). Go to the resources page for the URL of the journal.
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This information is provided for educational purposes only and does not replace or amend professional medical advice. Unless otherwise stated and credited, the content of Phoenix5 (P5) is by and the opinion of and copyright © 2000 Robert Vaughn Young. All Rights Reserved. P5 is at <http://www.phoenix5.org>. P5's policy regarding privacy and right to reprint are at <www.phoenix5.org/infopolicy>.