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From Phoenix5's Prostate Cancer Glossary
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Gleason Score

Abbreviations: GS

Definition: A system of grading prostate cancer cells to determine the best treatment and to predict how well a person is likely to do. A low Gleason score means the cancer cells are very similar to normal prostate cells; a high Gleason score means the cancer cells are very different from normal. (CNet) Named after the physician who developed a method of grading prostate cancer, it classifies the cellular differentiation of cancerous tissues. The less the cancerous cells appear like normal cells, the more malignant the cancer; two numbers, each from 1-5, are assigned successively to the two most predominant patterns of differentiation present in the examined tissue sample and are added together to produce the Gleason Score.

For more information: See differentiation. Also see Gleason's drawing of the five types of cells at Phoenix5.


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Definitions are provided for education only and are not medical advice. Created exclusively for Phoenix5. © 2002 Phoenix5.