Gleason Grade
Abbreviations: GG
Definition: The Gleason Grade evaluates how effectively the cells of any particular cancer are able to structure themselves into glands resembling those of the normal prostate. A tumor whose structure is nearly normal (well differentiated) will probably have a biological behavior relatively close to normal -- that is not very aggressively malignant. Gleason grading is from very well differentiated (grade 1) to very poorly differentiated (grade 5) is usually done for the most part by viewing the low magnification microscopic image of the cancer. A grade (number) is given to the most common pattern and then to the secondary parttern. These two numbers are added to give the Gleason Score, which will be between 2 (1+1) and 10 (5+5). There is an on-going discussion on the possible value of using a third (tertiary) grade.
For more information: See differentiation, Gleason Score, tertiary Gleason grade.
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Definitions are provided for education only and are not medical advice. Created exclusively for Phoenix5. © 2002 Phoenix5.
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