From the Phoenix5 Prostate Cancer Glossary Prostate Cancer Acronyms & Abbreviations Only Definitions are at www.phoenix5.org or in the Phoenix5 glossary booklet. NUMBERS 3D : three-dimensional 3DCRT : 3D conformal radiation therapy 3DEBRT : 3D external beam radiation therapy 3DRT : 3D radiation therapy 3DXBRT : 3D external beam radiation therapy 5AR : 5-alpha reductase A AAAH : atypical adenomatous hyperplasia AAT : androgen ablation therapy AAWR : antiandrogen withdrawal response ADT, ADT2, ADT3 : androgen deprivation therapy AFP : alpha-fetoprotein AFUD : American Foundation for Urologic Disease AG : aminoglutethimide AIPC, AIPCa : androgen-independent prostate cancer AJCC : American Joint Committee on Cancer AP : alkaline phosphatase ASAP : atypical small acinar proliferation AUS : artificial urinary sphincter B BAT : B-mode Acquisition & Targeting BMD : bone mineral density bNED : biochemical non-evidence of disease BOO : bladder outlet obstruction BPH : benign prostatic hyperplasia BpN : bisphosphonate BPSA, bPSA : baseline PSA BRM : biological response modifier BS : bone scan Bx : biopsy C CAB : combined or complete androgen blockade CAM : complementary and alternative medicine CaP : cancer of the prostate CAP, CAP-1 : carcinoembryonic antigen peptide CAT : computerized axial tomography CBC : complete blood count cc : cubic centimeter CEA : carcinoembryonic antigen CEBRT : conformal external beam radiation therapy CFR : Code of Federal Regulations CGA : chromogranin A CHB, CHB2, CHB3 : combined hormonal blockade CHT : combined hormonal therapy cNED : clinical non-evidence of disease COX-2 : cyclooxygenase-2 CPA : cyproterone acetate cPSA : complexed PSA CRT : conformal radiation therapy CT : computerized (axial) tomography CXBRT : conformal external beam radiation therapy CZ : central zone D DES : diethylstilbestrol DEXA: Dual Energy X-ray Absorptiometry DHT : dihydrotestosterone DNA : deoxyribonucleic acid DRE : digital rectal exam DT : doubling time Dx : diagnosis E EBRT, EBT : external beam (radiation) therapy ECE : extracapsular extension ED : erectile dysfunction EXBRT, EXBT : external beam (radiation) therapy F FDA : Food & Drug Administration FPSA, fPSA : free PSA G GG : Gleason Grade GI : gastrointestinal GnHR : gonadotropin-releasing hormone GS : Gleason score H HC : hydrocortisone HCM : hypercalcemia of malignancy HDK : high dose ketoconazole HDR : high dose rate HHS : Health & Human Services Administration HRPC : hormone refractory prostate cancer HT : hormone therapy I IAS : intermittent androgen suppression ICHT : intermittent combined hormone therapy IHT : intermittent hormone therapy IIEF : International Index of Erectile Function IMT, IMRT : intensity modulated radiation therapy IND : Investigational New Drug IRT : interstitial radiation therapy IUAC : International Union Against Cancer IV : intravenous IVP : intravenous pyelogram L LDH : lactase dehydrogenase LDK : low dose ketoconazole LHRH : luteinizing hormone-releasing hormone LRP, LP : laparoscopic (radical) prostatectomy LUTS : lower urinary tract symptoms M MO, M1 : metastasis stages MAB : maximal androgen blockade; monoclonal antibody MRI : magnetic resonance imaging MRSI : magnetic resonance spectroscopic imaging MSM : methyl sulfonyl methane MUSE : Medicated Urethral System for Erection MX, MO, M1 : metastasis stages N N0, N1, N2, N3 : node stages NCI : National Cancer Institute NDA : New Drug Application NDPSA : nondetectable PSA NG : newsgroup NHB, NHT : neoadjuvant hormone blockade or therapy NIH : National Institutes of Health NLM : National Library of Medicine NSAI : nonsteroidal aromatase inhibitor NSAID : nonsteroidal anti-inflammatory drug NSE : neuron-specific enolase NSRP, NSRRP : nerve-sparing retropubic radical prostatectomy O OTC : over-the-counter (drugs) P PAP : prostatic acid phosphatase PBT, PBRT : proton beam (radio)therapy PCa : prostate cancer PCAI : PCa Intimacy (email list) PD : poorly differentiated PDQ : Physician's Data Query PDT : photodynamic therapy PET : positron emission tomography PG : prostaglandin PHML : Prostate Help Mailing List PIN : prostatic intraepithelial or intraductal neoplasia PNI : perineural invasion PPML : Prostate Problems Mailing List PSA : prostate specific antigen PSA II : free PSA PSAD : PSA density PSADT : PSA doubling time PSAV : PSA velocity PSM, PSMA : prostate specific membrane antigen PT : proton therapy PZ : peripheral zone Q QL, QOL : quality of life R RP : radical prostatectomy RRP : radical retropubic prostatectomy RPP : radical perineal prostatectomy RT-PCR : reverse transcriptase polymerase chain reaction Rx : prescription S SAP : serum alkaline phosphatase SEER : Surveillance, Epidemiology, and Ends Results (NCI) SEPA : Soft Enhancer of Percutaneous Absorption SHIM : Sexual Health Inventory for Men SI : seed implantation Sm 153 : samarium 153 ST : serum testosterone SVI : seminal vesicle invasion Sx : symptoms SXA : Single Energy X-ray Absorptiometry T T1, T1a, b, c : tumor staging T2, T2a, b, c : tumor staging T3, T3a, b, c : tumor staging TAB : total androgen blockade THB : total hormonal blockade TNM : Tumor, Node Metastasis (staging) TRUS, TRUSP : transrectal ultrasound (of the prostate) TUMT : Transurethral Microwave Thermotherapy TUNA : transurethral needle ablation TUR : transurethral resection TURP : transurethral resection of the prostate Tx : treatment Tz : transition zone UV UA : urinalysis US : ultrasound UTI : urinary tract infection VED : vacuum erection device WXYZ WBC : white blood count WD : well-differentiated WW : watchful waiting XBR, XBRT : external beam radiation (therapy) YO : years old This information is provided for educational purposes only and does not replace or amend professional medical advice. Phoenix5 is at www.phoenix5.org. 12/29/02