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A Primer on Prostate Cancer
The Empowered Patient's Guide
by Stephen B. Strum, MD & Donna Pogliano
Table of Contents
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How to Use This Book
An Overview
Chapter 1: How to Proceed
Move Beyond Panic
Synergize Your Efforts
Understand Your Options
Understand the Inherent Biases
Know the Tempo of the Disease
Choosing a Doctor and a Treatment
Keep Meticulous Records
Be Aware of the Financial Side of Your Illness
Gathering Information
Nuts and Bolts
What You Should Have Learned from This Chapter
Chapter 2: The Basics of Prostate Cancer
How Does Prostate Cancer Work?
What You Should Have Learned from This Chapter
Chapter 3: Diagnosis and Testing
The PSA and the Free PSA Percentage
Digital Rectal Exam (DRE)
Biopsy of the Prostate and the Gleason Score
Prostatic Acid Phosphatase (PAP)
ProstaScint Scan
Endorectal MRI
DNA Ploidy
Positron Emission Tomography (PET) Scan
Bone Scan
CT (Computerized Tomography) Scan or CAT Scan
Chromogranin A (CGA)
Transforming Growth Factor Beta I (TGF-ß1)
What You Should Have Learned from This Chapter
Chapter 4: Treatment Options
Radical Prostatectomy (RP)
Pathological Examination
Debulking the Tumor
Addressing Lower Urinary Tract Symptoms
Risk of Impotence
Penile Shrinkage
Dry Orgasms
Incontinence
Anastomotic Stricture
Salvage Therapies
Cryosurgery (Cryotherapy, Cryoablation)
Cryosurgery Centers
Cryosurgery Results
Radiation Therapy (RT
Advances in RT
Overview
Brachytherapy
External Beam Radiation Therapy (EBRT)
Androgen Deprivation Therapy (ADT)
ADT Overview
Watchful Waiting or Objectified Observation
Chemotherapy of PC
Treatments on the Horizon
Aptosyn
Provenge
Angiostatin and Endostatin
Atrasentan: An Endothelin Receptor Antagonist
Oncolytic Viruses
Antisense Oligonucleotides (ASO)
Clinical Trials
What You Should Have Learned from This Chapter
Chapter 5: What You Should Have Learned From This Primer
Afterword
Acknowledgments
Appendix A: Resources
Introduction
To Educate You and Provide Guidance
To Contribute to your Knowledge Base
To Communicate at a Higher Level
with Your Medical Team
To Create a Personalized Assessment of Your Status
To Obtain Highly Focused Guidance
To Ask Your Doctor Questions
To Focus Further on Local Treatment Options
To Resolve Treatment Side-Effects and Prevent Them
To Employ Preventive and Wholistic Approaches
To Further Your Assistance
Appendix B: If You Want To Know More
Appendix C: The Partin Tables
Appendix D: Glossary and TNM Staging Definitions
Appendix E: References
Appendix F: Useful Forms
The Transrectal Ultrasound of the Prostate (TRUSP) Form
The Diagnostic Biopsy Form
The Biomarkers, Hormones, Bone Integrity and Other Labs Forms
The AUA Symptom Score Form
The Bone Scan Form
The PC Laboratory Form
The ProstaScint-CT Fusion Form
The Endorectal MRI with Spectroscopy Form
The Helpline Medical Form (HMF)
The Flow Sheet Form
The Summary Sheet and Surveillance Form
Appendix G: Clinical Stages of PC Illustrated
Appendix H: Figures, Tables, Physician's Notes, and Forms Listed
List of Figures
List of Tables
List of Physician's Notes
List of Forms
Index
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